skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Search for: All records

Creators/Authors contains: "Lu, Andrew"

Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?

Some links on this page may take you to non-federal websites. Their policies may differ from this site.

  1. Metacognition is widely acknowledged as a key soft skill in collaborative software development. The ability to plan, monitor, and reflect on cognitive and team processes is crucial to the efficient and effective functioning of a software team. To explore students' use of reflection--one aspect of metacognition--in undergraduate team software projects, we analyzed the online chat channels of teams participating in agile software development projects in two undergraduate courses that took place exclusively online (n = 23 teams, 117 students, and 4,915 chat messages). Teams' online chats were dominated by discussions of work completed and to be done; just two percent of all chat messages showed evidence of reflection. A follow-up analysis of chat vignettes centered around reflection messages (n = 63) indicates that three-fourths of the those messages were prompted by a course requirement; just 14\% arose organically within the context of teams' ongoing project work. Based on our findings, we identify opportunities for computing educators to increase, through pedagogical and technological interventions, teams' use of reflection in team software projects. 
    more » « less
  2. Abstract Cell therapies are emerging as a promising new therapeutic modality in medicine, generating effective treatments for previously incurable diseases. Clinical success of cell therapies has energized the field of cellular engineering, spurring further exploration of novel approaches to improve their therapeutic performance. Engineering of cell surfaces using natural and synthetic materials has emerged as a valuable tool in this endeavor. This review summarizes recent advances in the development of technologies for decorating cell surfaces with various materials including nanoparticles, microparticles, and polymeric coatings, focusing on the ways in which surface decorations enhance carrier cells and therapeutic effects. Key benefits of surface‐modified cells include protecting the carrier cell, reducing particle clearance, enhancing cell trafficking, masking cell‐surface antigens, modulating inflammatory phenotype of carrier cells, and delivering therapeutic agents to target tissues. While most of these technologies are still in the proof‐of‐concept stage, the promising therapeutic efficacy of these constructs from in vitro and in vivo preclinical studies has laid a strong foundation for eventual clinical translation. Cell surface engineering with materials can imbue a diverse range of advantages for cell therapy, creating opportunities for innovative functionalities, for improved therapeutic efficacy, and transforming the fundamental and translational landscape of cell therapies. 
    more » « less